<i>ABCB1</i> polymorphisms are Associated with Clozapine Plasma Levels in Psychotic Patients - Concepedia

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<i>ABCB1</i> polymorphisms are Associated with Clozapine Plasma Levels in Psychotic Patients

63

Citations

32

References

2009

Year

G. Consoli, Marianna Lastella, Antonio Ciapparelli, Mario Catena Dell’Osso, Laura Ciofi, Emanuele Guidotti, Romano Danesi, Liliana Dell’Osso, Mario Del Tacca, Antonello Di Paolo

Pharmacogenomics

Abstract

c.3435CC patients require higher clozapine doses to achieve the same plasma concentrations as CT or TT patients, and ABCB1 genotyping should be considered as a novel strategy that should improve drug use.

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