Differential effect of acetyltransferase expression on the genotoxicity of heterocyclic amines in CHO cells

New Giemsa method for the differential staining of sister chromatids

Paul Perry, Sheldon Wolff · Nature · 1974 · 3.2K citations

Biology, Cytogenetics, Genetics +3

pEF-BOS, a powerful mammalian expression vector

Seiichi Mizushima, Shigekazu Nagata · Nucleic Acids Research · 1990 · 1.6K citations · Full text

Protein Function, Signal Transduction, Protein Expression +6

Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines.

Marguerite A. Butler, M. Iwasaki, F. Peter Guengerich et al. · Proceedings of the National Academy of Sciences · 1989 · 638 citations · Full text

Metabolomic Profiling, Pharmacotherapy, Cytochrome P-450pa +16

A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-<i>b</i>]pyridine (PhIP)

Nobuyuki Ito, Ryohei Hasegawa, Masashi Sano et al. · Carcinogenesis · 1991 · 539 citations

Sister chromatid exchange as an indicator of mutagenesis

A.V. Carrano, Larry H. Thompson, Patricia A. Lindl et al. · Nature · 1978 · 502 citations

Chromatin, Cytogenetics, Genetics +5