Marguerite A. Butler

Phylogenetic Comparative Analysis: A Modeling Approach for Adaptive Evolution

Marguerite A. Butler, Aaron A. King · The American Naturalist · 2004 · 1.5K citations

Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines.

Marguerite A. Butler, M. Iwasaki, F. Peter Guengerich et al. · Proceedings of the National Academy of Sciences · 1989 · 638 citations · Full text

Metabolomic Profiling, Pharmacotherapy, Cytochrome P-450pa +16

Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites

Marguerite A. Butler, Nicholas P. Lang, J.F. Young et al. · Pharmacogenetics · 1992 · 418 citations

Chemoprevention Strategy, Human Populations, Metabolomic Profiling +19

Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps.

Nicholas P. Lang, Marguerite A. Butler, Joyce Massengill et al. · PubMed · 1994 · 392 citations

Chemoprevention Strategy, Metabolomic Profiling, Pathology +17

SHORT COMMUNICATION: Genotype/phenotype discordance for human arylamine <i>N</i>-acetyltransferase (NAT2) reveals a new slow-acetylator allele common in African-Americans

Douglas A. Bell, Jack A. Taylor, Marguerite A. Butler et al. · Carcinogenesis · 1993 · 291 citations