Concepedia

Degradable lipid nanoparticles with predictable in vivo siRNA delivery activity

Kathryn A. Whitehead, J. Robert Dorkin, Arturo J. Vegas, Philip Chang, Omid Veiseh, J. Matthews, Owen S. Fenton, Yunlong Zhang, Karsten Olejnik, Volkan Yesilyurt,

Nature Communications · 2014 · 617 citations · 34 references

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34

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

Mark E. Davis, Jonathan E. Zuckerman, Chung Hang Jonathan Choi et al. · Nature · 2010 · 2.5K citations · Full text

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Quantification of mRNA using real-time RT-PCR

Tania Nolan, Rebecca Hands, Stephen A. Bustin · Nature Protocols · 2006 · 2.3K citations

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Rational design of cationic lipids for siRNA delivery

Sean C. Semple, Akin Akinc, Jianxin Chen et al. · Nature Biotechnology · 2010 · 1.8K citations

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Maximizing the Potency of siRNA Lipid Nanoparticles for Hepatic Gene Silencing In Vivo**

Muthusamy Jayaraman, Steven M. Ansell, Barbara L. Mui et al. · Angewandte Chemie International Edition · 2012 · 1.2K citations · Full text

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A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

Akin Akinc, Andreas Zumbuehl, Michael S. Goldberg et al. · Nature Biotechnology · 2008 · 1.2K citations

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