Concepedia

Calpain inhibition mediates autophagy-dependent protection against polyglutamine toxicity

Fiona M. Menzies, Moisés Garcı́a-Arencibia, Sara Imarisio, Niamh C. O’Sullivan, Thomas C. Ricketts, Brianne A. Kent, Mala V. Rao, Wayne Lam, Zeyn W. Green-Thompson, Ralph A. Nixon,

Cell Death and Differentiation · 2014 · 120 citations · 40 references

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40

Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller et al. · Cell · 1996 · 3.1K citations · Full text

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A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila

Georg Dietzl, Doris Chen, Frank Schnorrer et al. · Nature · 2007 · 2.7K citations

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

Brinda Ravikumar, Zdenek Berger, J. Eric Davies et al. · Nature Genetics · 2004 · 2.3K citations · Full text

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α-Synuclein Is Degraded by Both Autophagy and the Proteasome

Julie L. Webb, Brinda Ravikumar, Jane T. Atkins et al. · Journal of Biological Chemistry · 2003 · 1.4K citations · Full text

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Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis

Shída Yousefi, Remo Perozzo, Inès Schmid et al. · Nature Cell Biology · 2006 · 1.3K citations

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