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Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop

Positive FeedbackSignal TransductionSignaling PathwayCell RegulationReceptor Tyrosine KinaseCancer Cell BiologyProtein PhosphorylationBreast CancerSystems BiologyMedicineCell BiologyCell SignalingTyrosine Phosphatase Shp2Tumor BiologyBreast Cancer Progression