Heike Brinkhaus

Glutamate receptors regulate actin-based plasticity in dendritic spines

Maria Fischer, Stefanie Kaech, Uta Wagner et al. · Nature Neuroscience · 2000 · 444 citations

Synaptic Plasticity, Dendritic Spines, Physiology +7

Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling

Adrian Britschgi, Anke Bill, Heike Brinkhaus et al. · Proceedings of the National Academy of Sciences · 2013 · 319 citations · Full text

Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop

Nicola Aceto, Nina Sausgruber, Heike Brinkhaus et al. · Nature Medicine · 2012 · 264 citations

Positive Feedback, Signal Transduction, Signaling Pathway +12

JAK2/STAT5 Inhibition Circumvents Resistance to PI3K/mTOR Blockade: A Rationale for Cotargeting These Pathways in Metastatic Breast Cancer

Adrian Britschgi, Rita Andraos, Heike Brinkhaus et al. · Cancer Cell · 2012 · 240 citations · Full text

Metastatic Breast Cancer, Signaling Pathway, Breast Oncology +10

The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα

Adrian Britschgi, Stephan Duss, Sungeun Kim et al. · Nature · 2017 · 151 citations · Full text

Breast Oncology, Developmental Biology, Signal Transduction +8