Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis

Nicola Aceto, Aditya Bardia, David T. Miyamoto, +17

Cell

Breast Cancer MetastasisTumor BiologyBreast OncologyOncologyTumor Heterogeneity +6

Neutrophils escort circulating tumour cells to enable cell cycle progression

Barbara M. Szczerba, Francesc Castro-Giner, Marcus Vetter, +13

Nature

Tumor BiologyOncologyGranulocyteMedicineImmunology +4

Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility

Min Yu, Aditya Bardia, Nicola Aceto, +21

Science

Breast OncologyPathologyCell CultureTumor BiologyOncology +19

E-cadherin is required for metastasis in multiple models of breast cancer

Veena Padmanaban, Ilona Krol, Yasir Suhail, +4

Nature

Breast OncologyOncologyMedicineMultiple ModelsCell-matrix Interaction +5

Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding

Sofia Gkountela, Francesc Castro-Giner, Barbara M. Szczerba, +11

Cell

A microfluidic device for label-free, physical capture of circulating tumor cell clusters

A. Fatih Sarioglu, Nicola Aceto, Nikola Kojić, +18

Nature Methods

Microfluidic DeviceEngineeringBiofabricationLab-on-a-chipBiomedical Analysis +8

Single-Cell RNA Sequencing Identifies Extracellular Matrix Gene Expression by Pancreatic Circulating Tumor Cells

David T. Ting, Ben S. Wittner, Matteo Ligorio, +24

Cell Reports

Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis

Richard Y. Ebright, Sooncheol Lee, Ben S. Wittner, +22

Science

The metastatic spread of breast cancer accelerates during sleep

Zoi Diamantopoulou, Francesc Castro-Giner, Fabienne D. Schwab, +11

Nature

Breast OncologyMedicineBreast CancerOncologyRadiation Oncology

Activation of Multiple Proto-oncogenic Tyrosine Kinases in Breast Cancer via Loss of the PTPN12 Phosphatase

Tingting Sun, Nicola Aceto, Kristen L. Meerbrey, +25

Cell

Breast OncologySignal TransductionReceptor Tyrosine KinaseProtein PhosphorylationBreast Cancer +7