E-cadherin is required for metastasis in multiple models of breast cancer

Veena Padmanaban, Ilona Krol, Yasir Suhail, +4

Nature

Breast OncologyOncologyMedicineMultiple ModelsCell-matrix Interaction +5

Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters

Kevin J. Cheung, Veena Padmanaban, Vanesa L. Silvestri, +8

Proceedings of the National Academy of Sciences

Breast OncologyBiological MicroenvironmentsMulticolor LineageCancer BiologyTumor Biology +16

Cancer cells educate natural killer cells to a metastasis-promoting cell state

Isaac S. Chan, Hildur Knútsdóttir, Gayathri Ramakrishnan, +8

The Journal of Cell Biology

Neuronal substance P drives metastasis through an extracellular RNA–TLR7 axis

Veena Padmanaban, Isabel Keller, Ethan S Seltzer, +3

Nature

Molecular NeuroscienceSignal TransductionSignaling PathwayMedicineNeuronal Substance P +7

A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs

Xuhang Liu, Wenbin Mei, Veena Padmanaban, +5

Molecular Cell

Nucleic Acid ChemistryBiochemistryNatural SciencesRna BiologyMolecular Biology +4

Organotypic culture assays for murine and human primary and metastatic-site tumors

Veena Padmanaban, Eloïse M. Grasset, Neil M. Neumann, +7

Nature Protocols

Tumor BiologyOrganotypic Culture AssaysHuman PrimaryTumoral PathologyEndocrine Oncology +6

Statin-induced GGPP depletion blocks macropinocytosis and starves cells with oncogenic defects

Zhihua Jiao, Huaqing Cai, Long Yu, +4

Proceedings of the National Academy of Sciences

Stabilization of E-cadherin adhesions by COX-2/GSK3β signaling is a targetable pathway in metastatic breast cancer

Kuppusamy Balamurugan, Dipak K. Poria, Saadiya W. Sehareen, +10

JCI Insight

Cell AdhesionCox-2/gsk3β SignalingCell DeathCancer BiologyCox-2 Inhibitor Celecoxib +19

On the role of p53 in the cellular response to aneuploidy

Akshay Narkar, Blake A. Johnson, Pandurang Bharne, +7

Cell Reports

Twist1-Induced Epithelial Dissemination Requires Prkd1 Signaling

Dan Georgess, Veena Padmanaban, Orit Katarina Sirka, +6

Cancer Research