Complex Catabolic Effects of Central Alpha-MSH Infusion in Rats of Altered Nutritional States: Differences from Leptin

Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice

Dennis Huszar, Catherine Lynch, Victoria Fairchild-Huntress et al. · Cell · 1997 · 3K citations · Full text

Medicine, Endocrinology, Neuroscience +11

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

Michael A. Cowley, James L. Smart, Marcelo Rubinstein et al. · Nature · 2001 · 2.3K citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans

Michael W. Schwartz, Elaine R. Peskind, Murray A. Raskind et al. · Nature Medicine · 1996 · 1K citations

Medicine, Endocrinology, Physiology +12

Leptin Increases Hypothalamic Pro-opiomelanocortin mRNA Expression in the Rostral Arcuate Nucleus

Michael W. Schwartz, Randy J. Seeley, Stephen C. Woods et al. · Diabetes · 1997 · 853 citations · Full text

Life Sciences, Endocrinology, Neuroscience +17

Diet-induced obese mice develop peripheral, but not central, resistance to leptin.

Margaret van Heek, Douglas S. Compton, C F France et al. · Journal of Clinical Investigation · 1997 · 750 citations · Full text

Medicine, Endocrinology, Nutritional Sciences +13