Tri- and tetra-substituted naphthalene diimides as potent G-quadruplex ligands

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

Nam W. Kim, Mieczyslaw A. Piatyszek, Karen R. Prowse et al. · Science · 1994 · 7.1K citations

Telomerase Activity, Pathology, Human Telomerase Activity +17

Creation of human tumour cells with defined genetic elements

William C. Hahn, Christopher M. Counter, Ante S. Lundberg et al. · Nature · 1999 · 2.3K citations

Tumor Biology, Human Cell, Tumor Heterogeneity +6

Crystal structure of parallel quadruplexes from human telomeric DNA

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Chromatin, Crystal Structure, Dna +4

Inhibition of telomerase by G-quartet DMA structures

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Chromatin, Genome Instability, Natural Sciences +6

Inhibition of telomerase limits the growth of human cancer cells

William C. Hahn, Sheila A. Stewart, Mary W. Brooks et al. · Nature Medicine · 1999 · 1K citations

Oncogenic Agent, Medicine, Cell Proliferation +10