Bioorganic & Medicinal Chemistry Letters · 2008 · 143 citations · 26 references
PharmacyChemistryMedicinal ChemistryDrug DiscoveryOrganic ChemistryStructure-activity RelationshipsG-quadruplex ChemistryLigand BindingLigand-based DesignMolecular DockingPotency OptimizationProtein-ligand DockingG-quadruplex Ligand BindingG-quadruplex RepeatsG-quadruplex StructureG-quadruplexes
26
Specific Association of Human Telomerase Activity with Immortal Cells and Cancer
Nam W. Kim, Mieczyslaw A. Piatyszek, Karen R. Prowse et al. · Science · 1994 · 7.1K citations
Creation of human tumour cells with defined genetic elements
William C. Hahn, Christopher M. Counter, Ante S. Lundberg et al. · Nature · 1999 · 2.3K citations
Medicine, Cancer Biology, Genetics +13
Inhibition of telomerase by G-quartet DMA structures
Alan M. Zahler, James R. Williamson, Thomas R. Cech et al. · Nature · 1991 · 1.1K citations
Inhibition of telomerase limits the growth of human cancer cells
William C. Hahn, Sheila A. Stewart, Mary W. Brooks et al. · Nature Medicine · 1999 · 1K citations
Medicine, Cell Biology, Oncology +12