Mekala Gunaratnam

Stabilization of G-Quadruplex DNA by Highly Selective Ligands via Click Chemistry

Adam D. Moorhouse, Ana Mafalda Santos, Mekala Gunaratnam et al. · Journal of the American Chemical Society · 2006 · 226 citations

Dna Nanotechnology, Medicinal Chemistry, Nucleic Acid Chemistry +13

Molecular Basis of Structure–Activity Relationships between Salphen Metal Complexes and Human Telomeric DNA Quadruplexes

N. Campbell, Nurul Huda Abd Karim, Gary N. Parkinson et al. · Journal of Medicinal Chemistry · 2011 · 217 citations

Potassium Ion Channel, Biochemistry, Telomerase Inhibitory Activity +13

Trisubstituted Acridines as G-quadruplex Telomere Targeting Agents. Effects of Extensions of the 3,6- and 9-Side Chains on Quadruplex Binding, Telomerase Activity, and Cell Proliferation

Michael J. Moore, Christoph Schultes, Javier Cuesta et al. · Journal of Medicinal Chemistry · 2005 · 200 citations · Full text

Structure-Based Design and Evaluation of Naphthalene Diimide G-Quadruplex Ligands As Telomere Targeting Agents in Pancreatic Cancer Cells

Marialuisa Micco, Gavin W. Collie, Aaron G. Dale et al. · Journal of Medicinal Chemistry · 2013 · 183 citations

Chemoprevention Strategy, Tetra-substituted Naphthalene Diimide, Chemical Biology +19

Targeting Multiple Effector Pathways in Pancreatic Ductal Adenocarcinoma with a G-Quadruplex-Binding Small Molecule

Chiara Marchetti, Katherine G. Zyner, Stephan A. Ohnmacht et al. · Journal of Medicinal Chemistry · 2018 · 150 citations · Full text