Concepedia

G-quadruplex Ligand Binding

G-Quadruplex Ligand Binding is a biochemical interaction process in which a small molecule selectively associates with a G-quadruplex nucleic acid structure through specific molecular recognition, stabilizing the higher-order conformation and modulating its biological function.

954

Publications

48.7K

Citations

3.2K

Authors

829

Institutions

Publications per year

2017–2026

399

Parents

Publications

954

Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells

Giulia Biffi, Marco Di Antonio, David Tannahill et al. · Nature Chemistry · 2013 · 603 citations

, , +14

Small-molecule interaction with a five-guanine-tract G-quadruplex structure from the human MYC promoter

Anh Tuân Phan, Vitaly Kuryavyi, Hai Yan Gaw et al. · Nature Chemical Biology · 2005 · 509 citations · Full text

, , +15

Highly Efficient G-Quadruplex Recognition by Bisquinolinium Compounds

Anne De Cian, Elsa DeLemos, Jean‐Louis Mergny et al. · Journal of the American Chemical Society · 2007 · 440 citations

, , +16

Potassium−Lead-Switched G-Quadruplexes: A New Class of DNA Logic Gates

Tao Li, Erkang Wang, Shaojun Dong · Journal of the American Chemical Society · 2009 · 400 citations

, , +13

NMR-Based Model of a Telomerase-Inhibiting Compound Bound to G-Quadruplex DNA

Oleg Yu. Fedoroff, Miguel Salazar, Haiyong Han et al. · Biochemistry · 1998 · 364 citations

, , +13

1–5 of 954

Authors

3.2K

  1. JM
    Jean‐Louis Mergny

    Inserm, France

    56 publications · 4K citations

    35

    h-index

  2. SN
    Stephen Neidle

    Institute of Cancer Research, United Kingdom

    48 publications · 4.5K citations

    34

    h-index

  3. MT
    Marie‐Paule Teulade‐Fichou

    Centre National de la Recherche Scientifique, France

    46 publications · 4K citations

    33

    h-index

  4. SB
    Shankar Balasubramanian

    University of Cambridge, United Kingdom

    34 publications · 3.6K citations

    30

    h-index

  5. DM
    David Monchaud

    Centre National de la Recherche Scientifique, France

    32 publications · 2.7K citations

    26

    h-index

1–5 of 3.2K

Institutions

829

  1. Centre National de la Recherche Scientifique

    Paris, France

    52 h-index

    495 publications

    31.9K citations

  2. Inserm

    Paris, France

    42 h-index

    313 publications

    19.4K citations

  3. Institut Curie

    Paris, France

    33 h-index

    147 publications

    10.7K citations

  4. Sun Yat-sen University

    Guangzhou, China

    32 h-index

    401 publications

    18.2K citations

  5. University of Cambridge

    Cambridge, United Kingdom

    31 h-index

    146 publications

    14.4K citations

  6. University of Naples Federico II

    Naples, Italy

    30 h-index

    214 publications

    9.3K citations

  7. Université de Bordeaux

    Bordeaux, France

    30 h-index

    165 publications

    7.2K citations

  8. Institut Européen de Chimie et Biologie

    Pessac, France

    30 h-index

    130 publications

    7.1K citations

1–8 of 829

Venues

  1. Journal of the American Chemical Society

    JACS · 55 publications · 6.7K citations

    45

    h-index

  2. Nucleic Acids Research

    56 publications · 4.2K citations

    39

    h-index

  3. Chemistry - A European Journal

    60 publications · 2.2K citations

    31

    h-index

  4. Chemical Communications

    ChemComm · 52 publications · 2.4K citations

    31

    h-index

  5. Journal of Medicinal Chemistry

    32 publications · 2.5K citations

    29

    h-index

1–5