Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer

Daniel Öhlund, Abram Handly-Santana, Giulia Biffi, +20

The Journal of Experimental Medicine

PathologyDistinct SubpopulationCancer BiologyTumor BiologyCaf Heterogeneity +15

Organoid Models of Human and Mouse Ductal Pancreatic Cancer

Sylvia F. Boj, Chang‐Il Hwang, Lindsey A. Baker, +45

Cell

Tumor BiologyPancreatic CancerPathologyOrganoid ModelsMedicine +2

Quantitative visualization of DNA G-quadruplex structures in human cells

Giulia Biffi, David Tannahill, John McCafferty, +1

Nature Chemistry

ChromatinDnaCell DivisionNatural SciencesDna Analysis +7

Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts

Ela Elyada, Mohan Bolisetty, Pasquale Laise, +19

Cancer Discovery

IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma

Giulia Biffi, Tobiloba E. Oni, Benjamin Spielman, +5

Cancer Discovery

Visualization and selective chemical targeting of RNA G-quadruplex structures in the cytoplasm of human cells

Giulia Biffi, Marco Di Antonio, David Tannahill, +1

Nature Chemistry

Selective Chemical TargetingHuman CellsRna G-quadruplex StructuresNatural SciencesGlycobiology +6

Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer

Nina G. Steele, Giulia Biffi, Samantha B. Kemp, +33

Clinical Cancer Research

Elevated Levels of G-Quadruplex Formation in Human Stomach and Liver Cancer Tissues

Giulia Biffi, David Tannahill, Jodi L. Miller, +2

PLoS ONE

Human Cultured CellsDna AnalysisLiver Cancer TissuesPathologyCancer Biology +18

An Intramolecular G-Quadruplex Structure Is Required for Binding of Telomeric Repeat-Containing RNA to the Telomeric Protein TRF2

Giulia Biffi, David Tannahill, Shankar Balasubramanian

Journal of the American Chemical Society

GeneticsGenomic MechanismMolecular BiologyMolecular GeneticsIntramolecular G-quadruplex Structure +15

Selective RNA Versus DNA G‐Quadruplex Targeting by In Situ Click Chemistry

Marco Di Antonio, Giulia Biffi, Angelica Mariani, +3

Angewandte Chemie International Edition

EngineeringMolecular BiologyClick ChemistryChemical BiologyNucleic Acid Chemistry +14