Bone-marrow-derived cells contribute to the recruitment of microglial cells in response to β-amyloid deposition in APP/PS1 double transgenic Alzheimer mice

‘Green mice’ as a source of ubiquitous green cells

Masaru Okabe, Masahito Ikawa, Katsuya Kominami et al. · FEBS Letters · 1997 · 2.6K citations

Life Sciences, Cell Biology, Molecular Biology +17

Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

Frédérique Bard, Catherine Cannon, Robin Barbour et al. · Nature Medicine · 2000 · 2K citations

Life Sciences, Neurology, Neuroscience +17

RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease

Shi Du Yan, Xi Chen, Jin Fu et al. · Nature · 1996 · 2K citations

Life Sciences, Neurobiology, Neuroscience +12

Mutant presenilins specifically elevate the levels of the 42 residue β-amyloid peptide in vivo: evidence for augmentation of a 42-specific γ secretase

Joanna L. Jankowsky, Daniel J. Fadale, Jeffrey C. Anderson et al. · Human Molecular Genetics · 2003 · 1.6K citations · Full text

Life Sciences, Neurology, Neuroscience +16

Accelerated Amyloid Deposition in the Brains of Transgenic Mice Coexpressing Mutant Presenilin 1 and Amyloid Precursor Proteins

David Borchelt, Tamara Ratovitski, Judy van Lare et al. · Neuron · 1997 · 1K citations

Life Sciences, Neurology, Neuroscience +17