Concepedia

The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir®: A change in direction in the search for a second generation HCV NS3 protease inhibitor

Frank Bennett, Yuhua Huang, Siska Hendrata, Raymond G. Lovey, Stéphane Bogen, Weidong Pan, Zhuyan Guo, Andrew Prongay, Kevin X. Chen, Ashok Arasappan,

Bioorganic & Medicinal Chemistry Letters · 2010 · 30 citations · 22 references

DOI

Concepts

References

22

The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994

Miriam J. Alter, Deanna Kruszon-Moran, Omana V. Nainan et al. · New England Journal of Medicine · 1999 · 3K citations · Full text

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Replication of Subgenomic Hepatitis C Virus RNAs in a Hepatoma Cell Line

Volker Lohmann, Frank Körner, Jan Oliver Koch et al. · Science · 1999 · 2.8K citations

, , +16

Hepatitis C Viral Dynamics in Vivo and the Antiviral Efficacy of Interferon-α Therapy

Avidan U. Neumann, Nancy P. Lam, Harel Dahari et al. · Science · 1998 · 2.1K citations

, , +17

Efficient Initiation of HCV RNA Replication in Cell Culture

Keril J. Blight, Alexander A. Kolykhalov, Charles M. Rice · Science · 2000 · 1.4K citations

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Peginterferon Alfa-2b or Alfa-2a with Ribavirin for Treatment of Hepatitis C Infection

John G. McHutchison, Eric Lawitz, Mitchell L. Shiffman et al. · New England Journal of Medicine · 2009 · 1.2K citations · Full text

, , +14