Kevin X. Chen

GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP)

F. Anthony Romero, Jeremy Murray, Kwong Wah Lai et al. · Journal of Medicinal Chemistry · 2017 · 125 citations · Full text

Discovery of Narlaprevir (SCH 900518): A Potent, Second Generation HCV NS3 Serine Protease Inhibitor

Ashok Arasappan, Frank Bennett, Stéphane Bogen et al. · ACS Medicinal Chemistry Letters · 2010 · 95 citations · Full text

Protease Inhibitors, Medicinal Chemistry, Synthetic Virology +11

Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300

Terry D. Crawford, F. Anthony Romero, Kwong Wah Lai et al. · Journal of Medicinal Chemistry · 2016 · 94 citations · Full text

Discovery and Structure−Activity Relationship of P₁−P₃ Ketoamide Derived Macrocyclic Inhibitors of Hepatitis C Virus NS3 Protease

Srikanth Venkatraman, Francisco Velázquez, Wanli Wu et al. · Journal of Medicinal Chemistry · 2008 · 52 citations · Full text

Analogue 52, Antiviral Compound, Hepatology +15

I. Novel HCV NS5B polymerase inhibitors: Discovery of indole 2-carboxylic acids with C3-heterocycles

G. Anilkumar, Charles A. Lesburg, Oleg Selyutin et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 49 citations

Biochemistry, Medicine, Indole 2-Carboxylic Acids +5