Kwong Wah Lai

GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP)

F. Anthony Romero, Jeremy Murray, Kwong Wah Lai et al. · Journal of Medicinal Chemistry · 2017 · 125 citations · Full text

Regio- and Enantioselective <i>Inter</i>molecular Rhodium-Catalyzed [2+2+2] Carbocyclization Reactions of 1,6-Enynes with Methyl Arylpropiolates

P. Andrew Evans, Kwong Wah Lai, James R. Sawyer · Journal of the American Chemical Society · 2005 · 124 citations · Full text

Cross-coupling Reaction, Methyl Arylpropiolates, Engineering +11

Discovery of a Potent and Selective in Vivo Probe (GNE-272) for the Bromodomains of CBP/EP300

Terry D. Crawford, F. Anthony Romero, Kwong Wah Lai et al. · Journal of Medicinal Chemistry · 2016 · 94 citations · Full text

Chemistry of aminophenols. Part 3: First synthesis of nitrobenzo[b]furans via a coupling–cyclization approach

Wei‐Min Dai, Kwong Wah Lai · Tetrahedron Letters · 2002 · 74 citations

Combinatorial Chemistry, First Synthesis, Engineering +6

Design of a brain-penetrant CDK4/6 inhibitor for glioblastoma

Sarah M. Bronner, Karl A. Merrick, Jeremy Murray et al. · Bioorganic & Medicinal Chemistry Letters · 2019 · 64 citations · Full text

Neuro-oncology, Medicine, Tumor Targeting +6