Concepedia

Design of a brain-penetrant CDK4/6 inhibitor for glioblastoma

Sarah M. Bronner, Karl A. Merrick, Jeremy Murray, Laurent Salphati, John G. Moffat, Jodie Pang, Christopher J. Sneeringer, Nicholas Dompe, Patrick Cyr, Hans E. Purkey,

Bioorganic & Medicinal Chemistry Letters · 2019 · 64 citations · 16 references

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16

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

Nature · 2008 · 7.8K citations · Full text

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<i>MGMT</i> Gene Silencing and Benefit from Temozolomide in Glioblastoma

Monika E. Hegi, Annie‐Claire Diserens, Thierry Gorlia et al. · New England Journal of Medicine · 2005 · 7.3K citations · Full text

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The Somatic Genomic Landscape of Glioblastoma

Cameron Brennan, Roel G.W. Verhaak, Aaron McKenna et al. · Cell · 2013 · 5.2K citations · Full text

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Cdk Phosphorylation Triggers Sequential Intramolecular Interactions that Progressively Block Rb Functions as Cells Move through G1

J. William Harbour, Robin X Luo, Angeline Dei Santi et al. · Cell · 1999 · 1.1K citations · Full text

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Moving beyond Rules: The Development of a Central Nervous System Multiparameter Optimization (CNS MPO) Approach To Enable Alignment of Druglike Properties

Travis T. Wager, Xinjun Hou, Patrick R. Verhoest et al. · ACS Chemical Neuroscience · 2010 · 1K citations

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