Concepedia

Zhuyan Guo

ZG

Statistics

Publications

50

Citations

3.3K

H-Index

30

Active since

1992

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

Scripps Research Institute

United States Military Academy

Molecular Oncology (United States)

Harvard University

Zhuyan Guo is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in pharmacology, drug discovery, and medicinal chemistry.

Publications per year

1992–2022

50

Publications

50

Kinetics of protein folding: Nucleation mechanism, time scales, and pathways

Zhuyan Guo, D. Thirumalai · Biopolymers · 1995 · 353 citations

, , +17

Discovery of (1 <i>R</i> ,5 <i>S</i> )- <i>N</i> -[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2( <i>S</i> )-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2( <i>S</i> )-carboxamide (SCH 503034), a Selective, Potent, Orally Bioavailable Hepatitis C Virus NS3 Protease Inhibitor:  A Potential Therapeutic Agent for the Treatment of Hepatitis C Infection

Srikanth Venkatraman, Stéphane Bogen, Ashok Arasappan et al. · Journal of Medicinal Chemistry · 2006 · 282 citations · Full text

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Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle

Paola Favuzza, Manuel de Lera Ruiz, Jennifer K. Thompson et al. · Cell Host & Microbe · 2020 · 165 citations · Full text

, , +17

Exploring the folding free energy surface of a three-helix bundle protein

Zhuyan Guo, Charles L. Brooks, Erik M. Boczko · Proceedings of the National Academy of Sciences · 1997 · 161 citations

, , +17

Toward Fast and Accurate Binding Affinity Prediction with pmemdGTI: An Efficient Implementation of GPU-Accelerated Thermodynamic Integration

Tai‐Sung Lee, Yuan Hu, Brad Sherborne et al. · Journal of Chemical Theory and Computation · 2017 · 139 citations

, , +17

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