Concepedia

Manuel de Lera Ruiz

MD

11

Publications

354

Citations

11

H-Index

2006

Active since

Affiliations

United States Military Academy(Current)

Merck & Co., Inc., Rahway, NJ, USA (United States)

The University of Melbourne

Walter and Eliza Hall Institute of Medical Research

The Ohio State University

Manuel de Lera Ruiz is an author at United States Military Academy specializing in medicine, pharmacology, and drug discovery.

Top concepts

MedicinePharmacologyDrug DiscoveryBiochemistryPharmacotherapyBiomolecular EngineeringImmunologyChemical BiologyNatural SciencesOrganic Chemistry

Publications per year

2006–2024

11

Publications

11

Dual Plasmepsin-Targeting Antimalarial Agents Disrupt Multiple Stages of the Malaria Parasite Life Cycle

Paola Favuzza, Manuel de Lera Ruiz, Jennifer K. Thompson et al. · Cell Host & Microbe · 2020 · 159 citations · Full text

Synthesis of a CGRP Receptor Antagonist via an Asymmetric Synthesis of 3-Fluoro-4-aminopiperidine

Carmela Molinaro, Eric M. Phillips, Bangping Xiang et al. · The Journal of Organic Chemistry · 2019 · 31 citations

Bioorganic Chemistry, Organic Chemistry, Peptide Science +22

Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax

Anthony N. Hodder, Janni Christensen, S.W. Scally et al. · Structure · 2022 · 27 citations

Plasmepsin Ix, Drug Selectivity, Antiparasitic Agent +11

Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic

Valerie W. Shurtleff, M. E. Layton, Craig A. Parish et al. · Journal of Medicinal Chemistry · 2024 · 23 citations

Immunology, Antiviral Drug, Viral Structural Protein +16

Discovery of MK‐8970: An Acetal Carbonate Prodrug of Raltegravir with Enhanced Colonic Absorption

Abbas M. Walji, Rosa I. Sánchez, Sophie‐Dorothée Clas et al. · ChemMedChem · 2014 · 22 citations

Pharmaceutical Science, Gastrointestinal Pharmacology, Immunology +17

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