Siska Hendrata

Discovery of (1 <i>R</i> ,5 <i>S</i> )- <i>N</i> -[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2( <i>S</i> )-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2( <i>S</i> )-carboxamide (SCH 503034), a Selective, Potent, Orally Bioavailable Hepatitis C Virus NS3 Protease Inhibitor:  A Potential Therapeutic Agent for the Treatment of Hepatitis C Infection

Srikanth Venkatraman, Stéphane Bogen, Ashok Arasappan et al. · Journal of Medicinal Chemistry · 2006 · 282 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of Prototype Peptidomimetic Agonists at the Human Melanocortin Receptors MC1R and MC4R

Carrie Haskell‐Luevano, Siska Hendrata, Cheryl North et al. · Journal of Medicinal Chemistry · 1997 · 99 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery of Narlaprevir (SCH 900518): A Potent, Second Generation HCV NS3 Serine Protease Inhibitor

Ashok Arasappan, Frank Bennett, Stéphane Bogen et al. · ACS Medicinal Chemistry Letters · 2010 · 98 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Cyclic Sulfones as Novel P3-Caps for Hepatitis C Virus NS3/4A (HCV NS3/4A) Protease Inhibitors: Synthesis and Evaluation of Inhibitors with Improved Potency and Pharmacokinetic Profiles

Francisco Velázquez, Mousumi Sannigrahi, Frank Bennett et al. · Journal of Medicinal Chemistry · 2010 · 70 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16

The introduction of P4 substituted 1-methylcyclohexyl groups into Boceprevir®: A change in direction in the search for a second generation HCV NS3 protease inhibitor

Frank Bennett, Yuhua Huang, Siska Hendrata et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 30 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12