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Discovery of adamantane ethers as inhibitors of 11β-HSD-1: Synthesis and biological evaluation

Jyoti Patel, Shuai Qi, Jürgen Dinges, Marty Winn, Marina Pliushchev, Steven Fung, Katina Monzon, William J. Chiou, Jiahong Wang, Liping Pan,

Bioorganic & Medicinal Chemistry Letters · 2006 · 41 citations · 12 references

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A Transgenic Model of Visceral Obesity and the Metabolic Syndrome

Hiroaki Masuzaki, J. Paterson, Hiroshi Shinyama et al. · Science · 2001 · 1.8K citations

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11β-Hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress

Yuri Kotelevtsev, Megan C. Holmes, Ann N. Burchell et al. · Proceedings of the National Academy of Sciences · 1997 · 855 citations

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Arylsulfonamidothiazoles as a New Class of Potential Antidiabetic Drugs. Discovery of Potent and Selective Inhibitors of the 11β-Hydroxysteroid Dehydrogenase Type 1

Tjeerd Barf, Jerk Vallgårda, Rikard Emond et al. · Journal of Medicinal Chemistry · 2002 · 211 citations · Full text

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Lack of tissue glucocorticoid reactivation in 11β-hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments

Joyce L.W. Yau, June Noble, Christopher J. Kenyon et al. · Proceedings of the National Academy of Sciences · 2001 · 189 citations · Full text

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Minireview: 11 -Hydroxysteroid Dehydrogenase Type 1-- A Tissue-Specific Amplifier of Glucocorticoid Action

Jonathan R. Seckl · Endocrinology · 2001 · 172 citations · Full text

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