Jerk Vallgårda

Arylsulfonamidothiazoles as a New Class of Potential Antidiabetic Drugs. Discovery of Potent and Selective Inhibitors of the 11β-Hydroxysteroid Dehydrogenase Type 1

Tjeerd Barf, Jerk Vallgårda, Rikard Emond et al. · Journal of Medicinal Chemistry · 2002 · 211 citations · Full text

Pharmaceutical Science, Selective Inhibitors, Pharmacotherapy +20

Intrinsic activity of enantiomers of 8-hydroxy-2-(di-n-propylamino)tetralin and its analogs at 5-hydroxytryptamine1A receptors that are negatively coupled to adenylate cyclase.

Linda J. Cornfield, David G. Lambert, L. -E. Arvidsson et al. · Molecular Pharmacology · 1991 · 106 citations

Discovery of a Potent, Orally Active 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor for Clinical Study: Identification of (<i>S</i>)-2-((1<i>S</i>,2<i>S</i>,4<i>R</i>)-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5<i>H</i>)-one (AMG 221)

Murielle M. Véniant, Clarence Hale, Randall W. Hungate et al. · Journal of Medicinal Chemistry · 2010 · 80 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Methyl Group +14

Active site variability of type 1 11β-hydroxysteroid dehydrogenase revealed by selective inhibitors and cross-species comparisons

Malin Hult, N. Shafqat, Björn Elleby et al. · Molecular and Cellular Endocrinology · 2006 · 39 citations

Type 1, Biochemistry, Cross-species Comparisons +4

Stereoselectivity and generality of the palladium-catalysed cyclopropanation of α,β-unsaturated carboxylic acids derivatized with Oppolzer's sultam

Jerk Vallgårda, Ulf Appelberg, I. Csöregh et al. · Journal of the Chemical Society Perkin Transactions 1 · 1994 · 37 citations

Palladium-catalysed Cyclopropanation, Engineering, Organic Chemistry +16