N. Shafqat

A non‐enzymatic function of 17β‐hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival

Katharina Rauschenberger, Katja Schöler, Jörn Oliver Sass et al. · EMBO Molecular Medicine · 2010 · 97 citations · Full text

Expanded substrate screenings of human and Drosophila type 10 17β-hydroxysteroid dehydrogenases (HSDs) reveal multiple specificities in bile acid and steroid hormone metabolism: characterization of multifunctional 3α/7α/7β/17β/20β/21-HSD

N. Shafqat, Hanns–Ulrich Marschall, Charlotta Filling et al. · Biochemical Journal · 2003 · 87 citations · Full text

Genetics, Hormone Metabolism, Cholic Acid +19

Crystal Structures of Human HMG-CoA Synthase Isoforms Provide Insights into Inherited Ketogenesis Disorders and Inhibitor Design

N. Shafqat, A.P. Turnbull, Johannes Zschocke et al. · Journal of Molecular Biology · 2010 · 79 citations

Inhibitor Design, Biochemistry, Biomolecular Structure Prediction +6

Human and rodent type 1 11�-hydroxysteroid dehydrogenases are 7�-hydroxycholesterol dehydrogenases involved in oxysterol metabolism

G. Tomas M. Hult, Björn Elleby, N. Shafqat et al. · Cellular and Molecular Life Sciences · 2004 · 74 citations · Full text

Oxysterol, Aldehyde Dehydrogenase, Biochemistry +12

Three-dimensional Structure and Enzymatic Function of Proapoptotic Human p53-inducible Quinone Oxidoreductase PIG3

Sergio Porté, Eva Valencia, Evgenia A Yakovtseva et al. · Journal of Biological Chemistry · 2009 · 65 citations · Full text