Hanns–Ulrich Marschall

Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist

Sama I. Sayin, Annika Wahlström, Jenny Felin et al. · Cell Metabolism · 2013 · 2.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial

Zobair M. Younossi, Vlad Ratziu, Rohit Loomba et al. · The Lancet · 2019 · 1.2K citations · Full text

Medicine, Internal Medicine, Pharmacology +8

Mesenchymal Stem Cells for Treatment of Therapy-Resistant Graft-versus-Host Disease

Olle Ringdén, Mehmet Uzunel, Ida Rasmusson et al. · Transplantation · 2006 · 1.1K citations

Life Sciences, Cell Biology, Immunology +15

A Placebo-Controlled Trial of Obeticholic Acid in Primary Biliary Cholangitis

Frederik Nevens, Pietro Andreoné, G. Mazzella et al. · New England Journal of Medicine · 2016 · 1.1K citations · Full text

Medicine, Pharmacology, Pharmacotherapy +16

Efficacy and Safety of the Farnesoid X Receptor Agonist Obeticholic Acid in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease

Sunder Mudaliar, Robert R. Henry, Arun J. Sanyal et al. · Gastroenterology · 2013 · 915 citations

Medicine, Endocrinology, Pharmacology +12