Concepedia

The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer

Alessandra Rustighi, Luca Tiberi, Alessia Soldano, Marco Napoli, Paolo Nucíforo, Antonio Rosato, Fred M. Kaplan, Anthony J. Capobianco, Salvatore Pece, Pier Paolo Di Fiore,

Nature Cell Biology · 2009 · 169 citations · 43 references

DOIFull text

Open access

Concepts

References

43

Tissue microarrays for high-throughput molecular profiling of tumor specimens

Juha Kononen, Lukas Bubendorf, Anne Kallionimeni et al. · Nature Medicine · 1998 · 4.1K citations

, , +11

A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain

Bart De Strooper, Wim Annaert, Philippe Cupers et al. · Nature · 1999 · 2.1K citations

, , +12

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

Eric H. Schroeter, Jeffrey A. Kisslinger, Raphael Kopan · Nature · 1998 · 1.6K citations

, , +13

Signalling downstream of activated mammalian Notch

Sophie Jarriault, Christel Brou, Frédérique Logeat et al. · Nature · 1995 · 1.4K citations

, , +9

Function of WW Domains as Phosphoserine- or Phosphothreonine-Binding Modules

Pei‐Jung Lu, Xiao Zhen Zhou, Minhui Shen et al. · Science · 1999 · 686 citations

, , +17