Concepedia

TCR‐mediated Erk activation does not depend on Sos and Grb2 in peripheral human T cells

Nicole Warnecke, Mateusz P. Poltorak, Bhavani S. Kowtharapu, Boerge Arndt, James C. Stone, Burkhart Schraven, Luca Simeoni

EMBO Reports · 2012 · 33 citations · 20 references

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20

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

László Buday, Julian Downward · Cell · 1993 · 1.1K citations

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Digital Signaling and Hysteresis Characterize Ras Activation in Lymphoid Cells

Jayajit Das, Mary Ho, Julie Zikherman et al. · Cell · 2009 · 411 citations · Full text

, , +13

RasGRP is essential for mouse thymocyte differentiation and TCR signaling

Nancy A. Dower, Stacey L. Stang, Drell A. Bottorff et al. · Nature Immunology · 2000 · 408 citations

, , +12

The duration, magnitude and compartmentalization of ERK MAP kinase activity: mechanisms for providing signaling specificity

Miki Ebisuya, Kunio Kondoh, Eisuke Nishida · Journal of Cell Science · 2005 · 335 citations

, , +14

RasGRP links T-cell receptor signaling to Ras

Julius O. Ebinu, Stacey L. Stang, Christine Teixeira et al. · Blood · 2000 · 314 citations

, , +12