Oral gene therapy for hemophilia B using chitosan‐formulated FIX mutants

Identification of stem cells in small intestine and colon by marker gene Lgr5

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Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

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Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B

Amit C. Nathwani, Edward G. D. Tuddenham, Savita Rangarajan et al. · New England Journal of Medicine · 2011 · 1.8K citations · Full text

Medicine, Hematology, Molecular Medicine +13

Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency

Hai‐Quan Mao, Krishnendu Roy, Vu L. Troung-Le et al. · Journal of Controlled Release · 2001 · 1.2K citations

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Oral gene delivery with chitosan–DNA nanoparticles generates immunologic protection in a murine model of peanut allergy

Krishnendu Roy, Hai‐Quan Mao, Shau Ku Huang et al. · Nature Medicine · 1999 · 1.1K citations

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