Efficacy and safety of trimodulin, a novel polyclonal antibody preparation, in patients with severe community-acquired pneumonia: a randomized, placebo-controlled, double-blind, multicenter, phase II trial (CIGMA study)

Tobias Welte, R. Phillip Dellinger, Henning Ebelt, +39

Intensive Care Medicine

Galectin-9 Is a Suppressor of T and B Cells and Predicts the Immune Modulatory Potential of Mesenchymal Stromal Cell Preparations

Christopher Ungerer, Patricia Quade-Lyssy, Heinfried H. Radeke, +5

Stem Cells and Development

Clinical ImmunologyAdaptive Immune SystemImmunologyImmune RegulationImmune Modulator +20

Improved Hepatic Gene Transfer by Using an Adeno-Associated Virus Serotype 5 Vector

Federico Mingozzi, Jörg Schüttrumpf, Valder R. Arruda, +5

Journal of Virology

Specific gene delivery to liver sinusoidal and artery endothelial cells

Tobias Abel, Ebtisam El Filali, Johan Waern, +12

Blood

INCREASED PREVALENCE OF A POLYMORPHISM IN THE GENE CODING FOR HUMAN PROTHROMBIN IN PATIENTS WITH CORONARY HEART DISEASE

Herbert Watzke, Jörg Schüttrumpf, Senta Graf, +2

Thrombosis Research

Genetic DeterminantCardiovascular EpidemiologyCardiovascular DiseaseMedicineGenetics +11

Chemical Chaperones Improve Protein Secretion and Rescue Mutant Factor VIII in Mice with Hemophilia A

Stefanie Roth, Jörg Schüttrumpf, Peter Milanov, +7

PLoS ONE

Protein SecretionMolecular BiologyOxidative StressHeme TraffickingInflammation +14

A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway

Bianca Helling, Martin König, Benjamin Dälken, +15

Immunology and Cell Biology

Engineered factor IX variants bypass FVIII and correct hemophilia A phenotype in mice

Peter Milanov, Lacramioara Ivanciu, Daniela Abriss, +7

Blood

Pneumolysin induces platelet destruction, not platelet activation, which can be prevented by immunoglobulin preparations in vitro

Kristin Jahn, Stefan Handtke, Raghavendra Palankar, +12

Blood Advances

Acute Lung InjuryInflammatory Lung DiseaseImmunoglobulin PreparationsLung InflammationImmunology +20

Functional relevance of in vivo half antibody exchange of an IgG4 therapeutic antibody-drug conjugate

Peter Herbener, Kurt Schönfeld, Martin König, +4

PLoS ONE

Immunocytochemical TechniqueAutoimmune DiseaseAllergyFunctional RelevanceWild Type +13