Concepedia

Effects of Bcl-2 modulation with G3139 antisense oligonucleotide on human breast cancer cells are independent of inherent Bcl-2 protein expression

Kim N., Anne E. Wallis, Chow Hwee Lee, Daniel Lopez de Menezes, Jason Sartor, Wieslawa H. Dragowska, Lawrence D. Mayer

Breast Cancer Research and Treatment · 2000 · 67 citations · 17 references

DOI

Concepts

References

17

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

David L. Vaux, Suzanne Cory, Jerry M. Adams · Nature · 1988 · 3.2K citations

, , +12

BCL-2 antisense therapy in patients with non-Hodgkin lymphoma

Andrew Webb, David Cunningham, Finbarr E. Cotter et al. · The Lancet · 1997 · 498 citations

, , +13

bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice

Burkhard Jansen, Hermine Schlagbauer‐Wadl, Bob D. Brown et al. · Nature Medicine · 1998 · 487 citations

, , +13

bcl-2 gene transfer increases relative resistance of S49.1 and WEHI7.2 lymphoid cells to cell death and DNA fragmentation induced by glucocorticoids and multiple chemotherapeutic drugs.

Toshiyuki Miyashita, John C. Reed · PubMed · 1992 · 480 citations

, , +15

Estrogen promotes chemotherapeutic drug resistance by a mechanism involving Bcl-2 proto-oncogene expression in human breast cancer cells.

Christine Teixeira, John C. Reed, M.A. Christine Pratt · PubMed · 1995 · 421 citations

, , +16