Lawrence D. Mayer

The Liposomal Formulation of Doxorubicin

Sheela A. Abraham, Dawn Waterhouse, Lawrence D. Mayer et al. · Methods in enzymology on CD-ROM/Methods in enzymology · 2005 · 413 citations

Lipid Preparation, Medicinal Chemistry, Medicine +4

Influence of vesicle size, lipid composition, and drug-to-lipid ratio on the biological activity of liposomal doxorubicin in mice.

Lawrence D. Mayer, Linda C.L. Tai, Dicken S. C. Ko et al. · PubMed · 1989 · 355 citations

Lipid Analysis, Proteinlipid Interaction, Lipid Preparation +12

In vivo maintenance of synergistic cytarabine:daunorubicin ratios greatly enhances therapeutic efficacy

Paul Tardi, Sharon A. Johnstone, Natashia Harasym et al. · Leukemia Research · 2008 · 349 citations

Daunorubicin Ratios, Pharmacology, Vivo Maintenance +7

Ratiometric dosing of anticancer drug combinations: Controlling drug ratios after systemic administration regulates therapeutic activity in tumor-bearing mice

Lawrence D. Mayer, Troy O. Harasym, Paul Tardi et al. · Molecular Cancer Therapeutics · 2006 · 324 citations · Full text

First-In-Man Study of CPX-351: A Liposomal Carrier Containing Cytarabine and Daunorubicin in a Fixed 5:1 Molar Ratio for the Treatment of Relapsed and Refractory Acute Myeloid Leukemia

Eric J. Feldman, Jeffrey E. Lancet, Jonathan E. Kolitz et al. · Journal of Clinical Oncology · 2011 · 299 citations · Full text