Troy O. Harasym

Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures

Sean C. Semple, Sandra K. Klimuk, Troy O. Harasym et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 2001 · 447 citations

Lipid Preparation, Proteinlipid Interaction, Biochemistry +7

In vivo maintenance of synergistic cytarabine:daunorubicin ratios greatly enhances therapeutic efficacy

Paul Tardi, Sharon A. Johnstone, Natashia Harasym et al. · Leukemia Research · 2008 · 349 citations

Daunorubicin Ratios, Pharmacology, Vivo Maintenance +7

Ratiometric dosing of anticancer drug combinations: Controlling drug ratios after systemic administration regulates therapeutic activity in tumor-bearing mice

Lawrence D. Mayer, Troy O. Harasym, Paul Tardi et al. · Molecular Cancer Therapeutics · 2006 · 324 citations · Full text

Immunogenicity and Rapid Blood Clearance of Liposomes Containing Polyethylene Glycol-Lipid Conjugates and Nucleic Acid

Sean C. Semple, Troy O. Harasym, Kathy A. Clow et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 209 citations

Leukemia-selective uptake and cytotoxicity of CPX-351, a synergistic fixed-ratio cytarabine:daunorubicin formulation, in bone marrow xenografts

Wah-Seng Lim, Paul Tardi, Nancy Dos Santos et al. · Leukemia Research · 2010 · 155 citations

Hematological Malignancy, Leukemia-selective Uptake, Medicine +9