Concepedia

PKB/Akt mediates cell-cycle progression by phosphorylation of p27Kip1 at threonine 157 and modulation of its cellular localization

Incheol Shin, F. Michael Yakes, Federico Rojo, Nah-Young Shin, Andrei V. Bakin, José Baselga, Carlos L. Arteaga

Nature Medicine · 2002 · 786 citations · 42 references

DOI

Concepts

References

42

Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor

Anne Brunet, Azad Bonni, Michael J. Zigmond et al. · Cell · 1999 · 6.6K citations · Full text

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Regulation of Cell Death Protease Caspase-9 by Phosphorylation

Michael H. Cardone, Natalie Roy, Henning R. Stennicke et al. · Science · 1998 · 3.1K citations

, , +17

Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt

Luis del Peso, Maribel González-Garcı́a, Carmen Page et al. · Science · 1997 · 2.2K citations

, , +17

Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization

J. Alan Diehl, Mangeng Cheng, Martine F. Roussel et al. · Genes & Development · 1998 · 2.1K citations · Full text

, , +17

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

Thomas Franke, Sung‐Il Yang, Tung O. Chan et al. · Cell · 1995 · 2K citations · Full text

, , +16