Tung O. Chan

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

Thomas Franke, Sung‐Il Yang, Tung O. Chan et al. · Cell · 1995 · 2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Akt activation by growth factors is a multiple-step process: the role of the PH domain

Alfonso Bellacosa, Tung O. Chan, Naheed N. Ahmed et al. · Oncogene · 1998 · 542 citations

Life Sciences, Biochemistry, Molecular Biology +15

Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

Naheed N. Ahmed, H. Leighton Grimes, Alfonso Bellacosa et al. · Proceedings of the National Academy of Sciences · 1997 · 526 citations

Life Sciences, Cell Biology, Immunology +17

Phosphatidylinositol 3-Kinase Is Required for Integrin-Stimulated AKT and Raf-1/Mitogen-Activated Protein Kinase Pathway Activation

W G King, Mark D. Mattaliano, Tung O. Chan et al. · Molecular and Cellular Biology · 1997 · 430 citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

Akt Is a Direct Target of the Phosphatidylinositol 3-Kinase

Ketaki Datta, Alfonso Bellacosa, Tung O. Chan et al. · Journal of Biological Chemistry · 1996 · 279 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16