Concepedia

Decreased levels of the cell-cycle inhibitor p27Kip1 protein: Prognostic implications in primary breast cancer

Charles Catzavelos, Nandita Bhattacharya, Yee Ung, James A. Wilson, Luba Roncari, Charanjit Sandhu, Patricia Shaw, Herman Yeger, Isabella Morava‐Protzner, Linda Kapusta,

Nature Medicine · 1997 · 843 citations · 14 references

DOI

Concepts

References

14

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

Hideo Toyoshima, Tony Hunter · Cell · 1994 · 2.1K citations

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p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest.

Kornélia Polyák, Jun‐ya Kato, Michael J. Solomon et al. · Genes & Development · 1994 · 2K citations · Full text

, , +17

Role of the Ubiquitin-Proteasome Pathway in Regulating Abundance of the Cyclin-Dependent Kinase Inhibitor p27

Michele Pagano, Sun W. Tam, Anne M. Theodoras et al. · Science · 1995 · 1.8K citations

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Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas

Massimo Loda, Barry Cukor, Sun W. Tam et al. · Nature Medicine · 1997 · 1K citations

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Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

Peggy L. Porter, Kathleen E. Malone, Patrick J. Heagerty et al. · Nature Medicine · 1997 · 918 citations

, , +14