Decreased levels of the cell-cycle inhibitor p27Kip1 protein: Prognostic implications in primary breast cancer

Charles Catzavelos, Nandita Bhattacharya, Yee Ung, +10

Nature Medicine

Breast OncologyMedicinePrimary Breast CancerBreast CancerPrognostic Implications +4

An experimentally derived confidence score for binary protein-protein interactions

Pascal Falter‐Braun, Murat Taşan, Matija Dreze, +17

Nature Methods

EngineeringInteractomicsNatural SciencesComputational BiologyProtein Modeling +7

Regulation of Planar Cell Polarity by Smurf Ubiquitin Ligases

Masahiro Narimatsu, Rohit Bose, Melanie Pye, +8

Cell

Signal TransductionMolecular RegulationMedicineCytoskeletonPlanar Cell Polarity +4

Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a transgenic mouse model of human gliomas.

Hao Ding, Luba Roncari, Patrick Shannon, +7

PubMed

PathologyHigh-grade GliomasTransgenic Mouse ModelCancer BiologyGlioma +16

Impact of oncogenes in tumor angiogenesis: Mutant K- <i>ras</i> up-regulation of vascular endothelial growth factor/vascular permeability factor is necessary, but not sufficient for tumorigenicity of human colorectal carcinoma cells

Futoshi Okada, Janusz Rak, Brad St. Croix, +6

Proceedings of the National Academy of Sciences

Expression of Activated Epidermal Growth Factor Receptors, Ras-Guanosine Triphosphate, and Mitogen-activated Protein Kinase in Human Glioblastoma Multiforme Specimens

Matthias M. Feldkamp, Matthias M. Feldkamp, Prateek Lala, +5

Neurosurgery

Loss of Neurofibromin Is Associated with Activation of RAS/MAPK and PI3-K/AKT Signaling in a Neurofibromatosis 1 Astrocytoma

Nelson C. Lau, Matthias M. Feldkamp, Luba Roncari, +4

Journal of Neuropathology & Experimental Neurology

Neurofibromin Is AssociatedCell DeathPathologyGliomaSocial Sciences +16

Oligodendrogliomas result from the expression of an activated mutant epidermal growth factor receptor in a RAS transgenic mouse astrocytoma model.

Hao Ding, Patrick Shannon, Nelson C. Lau, +7

PubMed

Neuro-oncologyOligodendrogliomas ResultDevelopmental BiologyTumor PhenotypeGlioma +11

A role for the TGFβ-Par6 polarity pathway in breast cancer progression

Alicia Viloria‐Petit, Laurent David, Jun Jia, +12

Proceedings of the National Academy of Sciences

Breast Cancer MetastasisTgfβ-par6 Polarity PathwayRadiation OncologyBreast OncologySignal Transduction +13

Inhibition of angiogenesis by blocking activation of the vascular endothelial growth factor receptor 2 leads to decreased growth of neurogenic sarcomas.

Lilyana Angelov, Bodour Salhia, Luba Roncari, +2

PubMed

ImmunologyPathologyVegf ReceptorGliomaTumor Biology +15