Convenient synthesis of tetrahydroisoquinoline-hydantoins

"Diversomers": an approach to nonpeptide, nonoligomeric chemical diversity.

Sheila H. DeWitt, John S. Kiely, Charles J. Stankovic et al. · Proceedings of the National Academy of Sciences · 1993 · 339 citations

Pharmacy, Chemistry, Medicinal Chemistry +14

Solid phase synthesis of hydantoins using a carbamate linker and a novel cyclization / cleavage step

Bruce A. Dressman, Larry A. Spangle, Stephen W. Kaldor · Tetrahedron Letters · 1996 · 209 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

Bicyclic Hydantoins with a Bridgehead Nitrogen. Comparison of Anticonvulsant Activities with Binding to the Neuronal Voltage-Dependent Sodium Channel

Wayne J. Brouillette, Vladimir P. Jestkov, Milton L. Brown et al. · Journal of Medicinal Chemistry · 1994 · 111 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Orthogonal Combinatorial Chemical Libraries

Benoît Déprez, Xavier Williard, Line Bourel‐Bonnet et al. · Journal of the American Chemical Society · 1995 · 93 citations

Pharmacy, Chemistry, Bioorthogonal Chemistry +5

Solution and solid phase synthesis of 5-alkoxyhydantoin libraries with a three-fold functional diversity

Stephen Hanessian, Rui‐Yang Yang · Tetrahedron Letters · 1996 · 86 citations

Pharmacy, Chemistry, Medicinal Chemistry +16