Christian Sergheraert

2- and 3-Substituted 1,4-Naphthoquinone Derivatives as Subversive Substrates of Trypanothione Reductase and Lipoamide Dehydrogenase from <i>Trypanosoma</i> <i>c</i><i>ruzi</i>:  Synthesis and Correlation between Redox Cycling Activities and in Vitro Cytotoxicity

Laurence Salmon-Chemin, Eric Buisine, Vanessa Yardley et al. · Journal of Medicinal Chemistry · 2001 · 256 citations · Full text

Design, synthesis and in vitro antimalarial activity of an acylhydrazone library

Patricia Melnyk, Christian Sergheraert, Philippe Grellier · Bioorganic & Medicinal Chemistry Letters · 2005 · 249 citations · Full text

Antifungal Agent, Biochemistry, Antiparasitic Agent +7

Truncated beta‐amyloid peptide species in pre‐clinical Alzheimer's disease as new targets for the vaccination approach

Nicolas Sergeant, Stepanie Bombois, Antoine Ghestem et al. · Journal of Neurochemistry · 2003 · 213 citations

Synthesis, Antimalarial Activity, and Molecular Modeling of New Pyrrolo[1,2-<i>a</i>]quinoxalines, Bispyrrolo[1,2-<i>a</i>]quinoxalines, Bispyrido[3,2-<i>e</i>]pyrrolo[1,2-<i>a</i>]pyrazines, and Bispyrrolo[1,2-<i>a</i>]thieno[3,2-<i>e</i>]pyrazines

Jean Guillon, Philippe Grellier, Mehdi Labaïed et al. · Journal of Medicinal Chemistry · 2004 · 168 citations

Antiparasitic Agent, Malaria, Organic Chemistry +18

Methylation-dependent T cell immunity to Mycobacterium tuberculosis heparin-binding hemagglutinin

Stéphane Temmerman, Kévin Pethe, Marcela Parra et al. · Nature Medicine · 2004 · 143 citations · Full text

Autoimmune Disease, Adaptive Immune System, Immunology +5