Milton L. Brown

A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma

Hayriye V. Erkizan, Yali Kong, Melinda S. Merchant et al. · Nature Medicine · 2009 · 435 citations · Full text

Oncogenic Agent, Pathology, Tumor Suppressor +4

Asymmetric Synthesis of 2,3-Dihydro-2-arylquinazolin-4-ones: Methodology and Application to a Potent Fluorescent Tubulin Inhibitor with Anticancer Activity

Gary M. Chinigo, Mikell Paige, Scott Grindrod et al. · Journal of Medicinal Chemistry · 2008 · 205 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Dhqz Analogues +13

AMP-activated protein kinase promotes human prostate cancer cell growth and survival

Hyeon Ung Park, Simeng Suy, Malika Danner et al. · Molecular Cancer Therapeutics · 2009 · 177 citations · Full text

Predicting New Indications for Approved Drugs Using a Proteochemometric Method

Sivanesan Dakshanamurthy, Naiem T. Issa, Shahin Assefnia et al. · Journal of Medicinal Chemistry · 2012 · 163 citations · Full text

Drug Target, Engineering, Hit Identification +20

High ALDH Activity Identifies Chemotherapy-Resistant Ewing's Sarcoma Stem Cells That Retain Sensitivity to EWS-FLI1 Inhibition

Ola Awad, Jason T. Yustein, Preeti Shah et al. · PLoS ONE · 2010 · 149 citations · Full text