Concepedia

RSPO2–LGR5 signaling has tumour-suppressive activity in colorectal cancer

Changjie Wu, Sunquan Qiu, Liting Lu, Jiawei Zou, Wenfeng Li, Ouchen Wang, Haina Zhao, Hongxiao Wang, Jiajia Tang, Lin Chen,

Nature Communications · 2014 · 127 citations · 44 references

DOIFull text

Open access

Concepts

References

44

Comprehensive molecular characterization of human colon and rectal cancer

Nature · 2012 · 8.7K citations · Full text

, , +16

Cancer Statistics, 2007

Ahmedin Jemal, Rebecca L. Siegel, Elizabeth Ward et al. · CA A Cancer Journal for Clinicians · 2007 · 7.5K citations · Full text

, , +16

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

Wim de Lau, Nick Barker, Teck Yew Low et al. · Nature · 2011 · 1.3K citations

, , +9

Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer

Hiromu Suzuki, D. Neil Watkins, Kam-Wing Jair et al. · Nature Genetics · 2004 · 1.1K citations

, , +17

ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner

Huai-Xiang Hao, Yang Xie, Yue Zhang et al. · Nature · 2012 · 976 citations

, , +8