Potent and Selective Thrombin Inhibitors Incorporating the Constrained Arginine Mimic <scp>l</scp>-3-Piperidyl(<i>N</i>-guanidino)alanine at P₁

Abstract

ADVERTISEMENT RETURN TO ISSUELetterNEXTPotent and Selective Thrombin Inhibitors Incorporating the Constrained Arginine Mimic l-3-Piperidyl(N-guanidino)alanine at P1Odile E. Levy, J. Edward Semple, Michael L. Lim, John Reiner, William E. Rote, Erin Dempsey, Brigitte M. Richard, Erli Zhang, Al Tulinsky, William C. Ripka, and Ruth F. NuttView Author Information Corvas International, Inc., 3030 Science Park Road, San Diego, California 92121-1102, and Department of Chemistry, Michigan State University, East Lansing, Michigan 48824-1322 Cite this: J. Med. Chem. 1996, 39, 23, 4527–4530Publication Date (Web):November 8, 1996Publication History Received23 August 1996Published online8 November 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/jm960607jhttps://doi.org/10.1021/jm960607jrapid-communicationACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views377Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Amides,Inhibitors,Molecular structure,Peptides and proteins,Selectivity Get e-Alerts