William C. Ripka

Structure-based Design of a Low Molecular Weight, Nonphosphorus, Nonpeptide, and Highly Selective Inhibitor of Protein-tyrosine Phosphatase 1B

Lars Iversen, Henrik Sune Andersen, Sven Branner et al. · Journal of Biological Chemistry · 2000 · 173 citations · Full text

Ptp1b Knockout Mice, Low Molecular Weight, Biochemistry +12

Discovery and SAR of a Novel Selective and Orally Bioavailable Nonpeptide Classical Competitive Inhibitor Class of Protein-Tyrosine Phosphatase 1B

Henrik Sune Andersen, Ole H. Olsen, Lars Iversen et al. · Journal of Medicinal Chemistry · 2002 · 131 citations · Full text

Drug Target, Selective Ptp1b Inhibitors, Protein-tyrosine Phosphatase 1B +16

Protein β-turn mimetics I. Design, synthesis, and evaluation in model cyclic peptides.

William C. Ripka, George V. De Lucca, A. Bach et al. · Tetrahedron · 1993 · 95 citations

Protein β-Turn Mimetics, Biochemistry, Natural Sciences +6

Computer modelling of the NAD binding site of ADP‐ribosylating toxins: active‐site structure and mechanism of NAD binding

Mario Domenighini, Cesare Montecucco, William C. Ripka et al. · Molecular Microbiology · 1991 · 73 citations

Design, Synthesis, and Evolution of a Novel, Selective, and Orally Bioavailable Class of Thrombin Inhibitors:  P1-Argininal Derivatives Incorporating P3-P4 Lactam Sulfonamide Moieties

J. Edward Semple, David Rowley, Terence K. Brunck et al. · Journal of Medicinal Chemistry · 1996 · 64 citations · Full text

P1-argininal Derivatives, Pharmaceutical Science, Thrombin Inhibitors +18