Phosphate ester derivatives of homocamptothecin: Synthesis, solution stabilities and antitumor activities

Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata^1,2

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Medicine, Medicinal Chemistry, Pharmacology +8

Synthesis of water-soluble (aminoalkyl)camptothecin analogs: inhibition of topoisomerase I and antitumor activity

William D. Kingsbury, Jeffrey C. Boehm, Dalia R. Jakas et al. · Journal of Medicinal Chemistry · 1991 · 516 citations

Medicine, Medicinal Chemistry, Pharmacology +10

Mechanism of Action of Camptothecin

Leroy F. Liu, Shyamal D. Desai, Tsai‐Kun Li et al. · Annals of the New York Academy of Sciences · 2000 · 473 citations

Medicine, Molecular Biology, Oncology +14

Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons.

Peter D’Arpa, Christopher Beardmore, Leroy F. Liu · PubMed · 1990 · 429 citations

Medicine, Cell Biology, Oncology +14

Differential Interactions of Camptothecin Lactone and Carboxylate Forms with Human Blood Components

Zihou Mi, Thomas G. Burke · Biochemistry · 1994 · 297 citations

Medicine, Biochemistry, Pharmacology +8