Wannian Zhang

New Tricks for an Old Natural Product: Discovery of Highly Potent Evodiamine Derivatives as Novel Antitumor Agents by Systemic Structure–Activity Relationship Analysis and Biological Evaluations

Guoqiang Dong, Shengzheng Wang, Zhenyuan Miao et al. · Journal of Medicinal Chemistry · 2012 · 185 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Selection of Evodiamine as a Novel Topoisomerase I Inhibitor by Structure-Based Virtual Screening and Hit Optimization of Evodiamine Derivatives as Antitumor Agents

Guoqiang Dong, Chunquan Sheng, Shengzheng Wang et al. · Journal of Medicinal Chemistry · 2010 · 150 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Three-Dimensional Model of Lanosterol 14α-Demethylase from <i>Cryptococcus neoformans</i> : Active-Site Characterization and Insights into Azole Binding

Chunquan Sheng, Zhenyuan Miao, Haitao Ji et al. · Antimicrobial Agents and Chemotherapy · 2009 · 115 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Small Molecule Inhibitors Simultaneously Targeting Cancer Metabolism and Epigenetics: Discovery of Novel Nicotinamide Phosphoribosyltransferase (NAMPT) and Histone Deacetylase (HDAC) Dual Inhibitors

Guoqiang Dong, Wei Chen, Xia Wang et al. · Journal of Medicinal Chemistry · 2017 · 106 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Discovery of Janus Kinase 2 (JAK2) and Histone Deacetylase (HDAC) Dual Inhibitors as a Novel Strategy for the Combinational Treatment of Leukemia and Invasive Fungal Infections

Yahui Huang, Guoqiang Dong, Huanqiu Li et al. · Journal of Medicinal Chemistry · 2018 · 97 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17