Peter D’Arpa

Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons.

Peter D’Arpa, Christopher Beardmore, Leroy F. Liu · PubMed · 1990 · 429 citations

Nucleic Acid Synthesis, Apoptosis, Molecular Biology +18

Ubiquitin-dependent Destruction of Topoisomerase I Is Stimulated by the Antitumor Drug Camptothecin

Shyamal D. Desai, Leroy F. Liu, Dolores Vázquez‐Abad et al. · Journal of Biological Chemistry · 1997 · 262 citations · Full text

cDNA cloning of human DNA topoisomerase I: catalytic activity of a 67.7-kDa carboxyl-terminal fragment.

Peter D’Arpa, P S Machlin, Harry Ratrie et al. · Proceedings of the National Academy of Sciences · 1988 · 260 citations · Full text

67.7-Kda Carboxyl-terminal Fragment, Protein Expression, Nucleic Acid Chemistry +15

The involvement of active DNA synthesis in camptothecin-induced G2 arrest: altered regulation of p34cdc2/cyclin B.

Yeou Ping Tsao, Peter D’Arpa, Leroy F. Liu · PubMed · 1992 · 209 citations

Dna Damage, Molecular Regulation, Molecular Biology +19

A model for tumor cell killing by topoisomerase poisons.

Hui Zhang, Peter D’Arpa, Leroy F. Liu · PubMed · 1990 · 171 citations