Follicular Helper T Cell Differentiation Requires Continuous Antigen Presentation that Is Independent of Unique B Cell Signaling

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene

Daisuke Kitamura, Jürgen Roes, Ralf Kühn et al. · Nature · 1991 · 1.8K citations

Life Sciences, Genetics, Immunology +12

Bcl6 and Blimp-1 Are Reciprocal and Antagonistic Regulators of T Follicular Helper Cell Differentiation

Robert J. Johnston, Amanda C. Poholek, Daniel DiToro et al. · Science · 2009 · 1.6K citations

Life Sciences, Immunology, Molecular Biology +17

Defective TCR expression in transgenic mice constructed using cDNA‐based α‐ and β‐chain genes under the control of heterologous regulatory elements

Megan Barnden, Jan Allison, William R. Heath · Immunology and Cell Biology · 1998 · 1.5K citations

Life Sciences, Immunology, Molecular Biology +15

Bcl6 Mediates the Development of T Follicular Helper Cells

Roza Nurieva, Yeonseok Chung, Gustavo Martínez et al. · Science · 2009 · 1.5K citations · Full text

Life Sciences, Developmental Biology, Immunology +17

Follicular B Helper T Cells Express Cxc Chemokine Receptor 5, Localize to B Cell Follicles, and Support Immunoglobulin Production

Dagmar Breitfeld, Lars Ohl, Elisabeth Kremmer et al. · The Journal of Experimental Medicine · 2000 · 1.4K citations · Full text

Life Sciences, Cell Biology, Immunology +17