A Primitive T Cell-Independent Mechanism of Intestinal Mucosal IgA Responses to Commensal Bacteria

Andrew J. Macpherson, Dominique Gatto, Elizabeth Sainsbury, +3

Science

DysbiosisImmunologyGastroenterologyImmunotherapyHost Immune Response +18

Follicular Helper T Cell Differentiation Requires Continuous Antigen Presentation that Is Independent of Unique B Cell Signaling

Elissa K. Deenick, Anna Chan, S. Cindy, +4

Immunity

Autoimmune DiseaseLymphocyte DevelopmentAdaptive Immune SystemImmunologyAntigen Processing +8

B cell priming for extrafollicular antibody responses requires Bcl-6 expression by T cells

Sau K. Lee, Robert J. Rigby, Dimitra Zotos, +12

The Journal of Experimental Medicine

Guidance of B Cells by the Orphan G Protein-Coupled Receptor EBI2 Shapes Humoral Immune Responses

Dominique Gatto, Didrik Paus, Antony Basten, +2

Immunity

Autoimmune DiseaseHumoral ResponseImmunologyB CellsImmunologic Mechanism +7

VSIG4, a B7 family-related protein, is a negative regulator of T cell activation

L. Vogt, Nicole Schmitz, Michael Kurrer, +10

Journal of Clinical Investigation

Negative RegulatorVsig4-ig Fusion MoleculesT-regulatory CellImmunologyImmune Regulation +16

Antigen Affinity Controls Rapid T-Dependent Antibody Production by Driving the Expansion Rather than the Differentiation or Extrafollicular Migration of Early Plasmablasts

Tyani D. Chan, Dominique Gatto, Katherine C. Wood, +3

The Journal of Immunology

Lymphocyte DevelopmentImmunologyImmunodominanceImmunologic MechanismAntigen Processing +17

The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells

Dominique Gatto, Katherine C. Wood, Irina Caminschi, +5

Nature Immunology

Splenic Dendritic CellsChemotactic Receptor Ebi2ImmunologyImmunological FunctionCell Death +10

The brain as an immune privileged site: dendritic cells of the central nervous system inhibit T cell activation

Tobias Suter, Gregoire Biollaz, Dominique Gatto, +4

European Journal of Immunology

Carrier induced epitopic suppression of antibody responses induced by virus-like particles is a dynamic phenomenon caused by carrier-specific antibodies

Andrea Jegerlehner, Melanie Wiesel, Klaus Dietmeier, +4

Vaccine

VaccinationVaccine TargetImmunologyCarrier-specific AntibodiesAntiviral Response +8

EBI2 Operates Independently of but in Cooperation with CXCR5 and CCR7 To Direct B Cell Migration and Organization in Follicles and the Germinal Center

Dominique Gatto, Katherine C. Wood, Robert Brink

The Journal of Immunology

ImmunologyImmunologic MechanismImmunotherapyCellular PhysiologyB Cell Localization +14