Concepedia

Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis

Masato Enari, Robert V. Talanian, Winnie W. Wrong, Shigekazu Nagata

Nature · 1996 · 982 citations · 29 references

DOI

Concepts

References

29

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Donald W. Nicholson, Ambereen Ali, Nancy A. Thornberry et al. · Nature · 1995 · 4K citations

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The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

Naoto Itoh, Shin Yonehara, Ai Ishii et al. · Cell · 1991 · 2.8K citations

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Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

Yuri Lazebnik, Scott H. Kaufmann, Serge Desnoyers et al. · Nature · 1994 · 2.6K citations

, , +10

A novel heterodimeric cysteine protease is required for interleukin-1βprocessing in monocytes

Nancy A. Thornberry, Herbert G. Bull, Jimmy Calaycay et al. · Nature · 1992 · 2.6K citations

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Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

Muneesh Tewari, Long T. Quan, Karen O’Rourke et al. · Cell · 1995 · 2.4K citations · Full text

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