Concepedia

Pro-apoptotic Proteins

Pro-Apoptotic Proteins is a class of regulatory proteins that induce programmed cell death by promoting mitochondrial outer membrane permeabilization and activating caspase cascades in response to cellular stress or damage signals.

4.4K

Publications

274.3K

Citations

25.9K

Authors

4.1K

Institutions

Publications per year

2017–2026

1.2K

Parents

Publications

4.4K

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell · 1997 · 7.3K citations · Full text

, , +17

The Pathophysiology of Mitochondrial Cell Death

Douglas R. Green, Guido Kroemer · Science · 2004 · 3.4K citations

, , +17

PUMA, a Novel Proapoptotic Gene, Is Induced by p53

Katsunori Nakano, Karen H. Vousden · Molecular Cell · 2001 · 2.3K citations · Full text

, , +14

Noxa, a BH3-Only Member of the Bcl-2 Family and Candidate Mediator of p53-Induced Apoptosis

Eri Oda, Rieko Ohki, Hideki Murasawa et al. · Science · 2000 · 2.1K citations

, , +16

ABT-263: A Potent and Orally Bioavailable Bcl-2 Family Inhibitor

Christin Tse, Alexander R. Shoemaker, Jessica Adickes et al. · Cancer Research · 2008 · 2K citations · Full text

, , +16

1–5 of 4.4K

Authors

25.9K

  1. AS
    Andreas Strasser

    Walter and Eliza Hall Institute of Medical Research, Australia

    24 publications · 1.3K citations

    21

    h-index

  2. GK
    Guido Kroemer

    Institut Gustave Roussy, France

    20 publications · 9.3K citations

    20

    h-index

  3. JC
    John C. Reed

    Sanford Burnham Prebys Medical Discovery Institute, United States

    16 publications · 6K citations

    16

    h-index

  4. DC
    David C.S. Huang

    Walter and Eliza Hall Institute of Medical Research, Australia

    15 publications · 1.3K citations

    15

    h-index

  5. JH
    Jochen H.M. Prehn

    Royal College of Surgeons in Ireland, Ireland

    15 publications · 666 citations

    14

    h-index

1–5 of 25.9K

Institutions

4.1K

  1. Harvard University

    Cambridge, United States

    47 h-index

    252 publications

    30.1K citations

  2. Inserm

    Paris, France

    46 h-index

    550 publications

    36.7K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    45 h-index

    465 publications

    51.7K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    35 h-index

    101 publications

    61.3K citations

  5. Walter and Eliza Hall Institute of Medical Research

    Melbourne, Australia

    34 h-index

    333 publications

    19.1K citations

  6. National Institutes of Health

    Bethesda, United States

    30 h-index

    108 publications

    11.2K citations

  7. Johns Hopkins University

    Baltimore, United States

    28 h-index

    125 publications

    22.2K citations

  8. The University of Melbourne

    Melbourne, Australia

    27 h-index

    242 publications

    10.9K citations

1–8 of 4.1K

Venues

  1. Journal of Biological Chemistry

    JBC · 305 publications · 35.1K citations

    109

    h-index

  2. PLoS ONE

    214 publications · 9.4K citations

    50

    h-index

  3. Cell Death and Disease

    96 publications · 4.4K citations

    45

    h-index

  4. Scientific Reports

    92 publications · 4.2K citations

    40

    h-index

  5. PubMed

    Repository · 159 publications · 6K citations

    39

    h-index

1–5